ASCP-MLT Questions & Answers & ASCP-MLT Study Guide & ASCP-MLT Exam Preparation

ASCP ASCP-MLT : MEDICAL LABORATORY TECHNICIAN - MLT(ASCP)

Exam Code: ASCP-MLT

Exam Name: MEDICAL LABORATORY TECHNICIAN - MLT(ASCP)

Updated: Aug 09, 2026

Q & A: 562 Questions and Answers

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ASCP ASCP-MLT Exam Syllabus Topics:

SectionObjectives
Urinalysis and Body Fluids- Fluid analysis and interpretation
  • 1. CSF and other body fluids
    • 2. Urine chemical and microscopic examination
      Clinical Chemistry- Metabolic and analytical testing
      • 1. Endocrine and metabolic panels
        • 2. Enzymes and electrolytes
          Blood Banking / Immunohematology- Blood group systems and antibody identification
          • 1. Crossmatching procedures
            • 2. ABO and Rh systems
              Hematology- Blood cell analysis and disorders
              • 1. Anemias and leukemias overview
                • 2. CBC and differential interpretation
                  Microbiology- Clinical microbiological techniques
                  • 1. Bacteriology and organism identification
                    • 2. Culture and sensitivity testing
                      Laboratory Operations- Quality and safety in the clinical lab
                      • 1. Quality control and assurance
                        • 2. Laboratory safety and regulations

                          ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

                          1. The recommended disinfectant for blood and body fluid contamination is:

                          A) hydrogen peroxide.
                          B) sodium hypochlorite.
                          C) antimicrobial soap.
                          D) sodium hydroxide.


                          2. The DAT, or direct antiglobulin test, is used to detect antibodies coating RBC's in vivo.
                          The Direct Antiglobulin Test (DAT) is usually used to detect:

                          A) Antigens in the plasma
                          B) Antibody-hapten reactions
                          C) Antibodies coating red cells
                          D) Antigens coating red cells
                          E) Antibodies in the plasma


                          3. The parents will each give one of their ABO genes, so the possibilities are as follows:
                          AB, AO, AB, AO = 50% chance of A blood type, 50% chance of AB blood type Blood Bank If parents have the blood group genotypes AA and BO, what is the possibility of having a child with a blood type of A?

                          A) 75%
                          B) none of them
                          C) 25%
                          D) 50%
                          E) 100%


                          4. The results of this PT and aPTT are in normal range. These results can be reported and are not indicative of the need to: order a mixing study or request a redraw.
                          You have just performed stat PT and aPTT tests on your coagulation instrument. Your results are as follows:
                          PT = 12 seconds (normal range 10-13 seconds)
                          aPTT = 24 seconds (normal range 21-34 seconds)
                          What would be your next step?

                          A) Report the results
                          B) Perform a mixing study
                          C) Request a redraw of the specimen


                          5. Since cimetidine inhibits CYP2D6, less amphetamine will probably need to be given since it will not be able to be metabolized as readily.
                          Most drug interactions are like this: one drug inhibits or competes with the same CYP450 as another drug. The end result is that higher concentrations of one, or both, drugs are present, leading to potential toxicity.
                          A patient is taking cimetidine for a stomach ulcer. This drug inhibits CYP2D6. The patient is now prescribed amphetamine for narcolepsy. Amphetamine is metabolized by CYP2D6. What would you predict?

                          A) Nothing can be assumed until you know the patient's status (PM, EM, UM).
                          B) The two drugs can never be given together since they interact.
                          C) The dose for the amphetamine needs to be lower than normal.
                          D) The dose for amphetamine needs to be higher than normal.


                          Solutions:

                          Question # 1
                          Answer: B
                          Question # 2
                          Answer: C
                          Question # 3
                          Answer: D
                          Question # 4
                          Answer: A
                          Question # 5
                          Answer: C

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